Description

Aminooxy-Peg1-Azide is a heterobifunctional crosslinker featuring an aminooxy group and an azide moiety, connected by a short polyethylene glycol (PEG) spacer. This compound is specifically engineered for efficient and selective bioconjugation, enabling the stable linkage of biomolecules under mild conditions. It is an essential reagent for researchers and manufacturers in biopharmaceutical development, proteomics, and advanced materials science, where precise and reliable chemical modification is paramount.

Application

• Bioconjugation and Protein Labeling: Site-specific modification of antibodies, proteins, and peptides via oxime ligation with carbonyl groups and azide-alkyne cycloaddition.
• ADC (Antibody-Drug Conjugate) Development: Facilitating the construction of stable, homogeneous linker-payload constructs for targeted cancer therapies.
• Surface Functionalization: Immobilization of biomolecules onto azide-modified or aldehyde-presenting surfaces for biosensor and microarray fabrication.
• Polymer Chemistry: Serving as a functional monomer or crosslinking agent for synthesizing smart hydrogels and functional polymeric materials.
• Chemical Biology Probes: Synthesis of activity-based probes and affinity tags for studying protein function and interactions.
• Diagnostic Reagent Synthesis: Creating conjugated reagents for immunoassays, fluorescence imaging, and other diagnostic platforms.

Basic Information

Product Name	Aminooxy-Peg1-Azide
CAS No.	2100306-70-3
Molecular Formula	C7H14N4O3
Molecular Weight	202.21 g/mol
Synonyms	1-Azido-2-(2-(2-aminooxyethoxy)ethoxy)ethane; Azido-PEG1-aminooxy; Aminooxy-PEG1-N3; O-(2-Azidoethoxy)ethylhydroxylamine; 2-[2-(2-Azidoethoxy)ethoxy]hydroxylamine; Aminooxy-PEG-azide; Azido-PEG-aminooxy; Aminooxy-PEG1-azide reagent
EINECS	Contact for details

Quality Control

Our Aminooxy-Peg1-Azide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance for critical research and GMP applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) in a dry, cool place. Due to its hygroscopic and moisture-sensitive nature, the container should be allowed to reach room temperature before opening to minimize condensation and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.