Description

Aminooxy-Peg4-Azide is a heterobifunctional polyethylene glycol (PEG) crosslinker featuring an aminooxy group and an azide moiety. This compound is essential for creating stable, site-specific bioconjugates through oxime ligation and copper-free click chemistry. It is primarily utilized by researchers and manufacturers in biopharmaceutical development, diagnostic assay production, and advanced materials science for labeling, immobilization, and polymer modification.

Application

• Bioconjugation and Protein/Peptide Modification: Site-specific labeling of antibodies, proteins, and peptides via oxime ligation with carbonyl-containing molecules.
• ADC (Antibody-Drug Conjugate) Development: Facilitating the stable, controlled attachment of cytotoxic payloads to antibodies for targeted cancer therapies.
• Surface Functionalization and Immobilization: Modifying sensor chips, nanoparticles, or solid supports for biosensor and diagnostic device fabrication.
• Polymer Chemistry and Materials Science: Serving as a versatile building block for synthesizing functionalized hydrogels, smart polymers, and drug delivery systems.
• Fluorescent Probe and Diagnostic Reagent Synthesis: Conjugating dyes, quenchers, or other reporter molecules to biomolecules for imaging and detection applications.
• Click Chemistry Applications: Enabling copper-free strain-promoted azide-alkyne cycloaddition (SPAAC) for bioorthogonal labeling in live cells.

Basic Information

Product Name	Aminooxy-Peg4-Azide
CAS No.	2100306-61-2
Molecular Formula	C17H34N6O7
Molecular Weight	434.5 g/mol
Synonyms	Azido-PEG4-aminooxy; Aminooxy-PEG4-N3; 2-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethoxy]ethyl (aminooxy)acetate; 17-Azido-3,6,9,12-tetraoxa-16-azaheptadecyloxyamine; O2-(Azido-PEG4)-hydroxylamine; Aminooxy-PEG4-azide; Aminooxy-PEG4-N3; Azido-PEG4-ONH2
EINECS	Contact for details

Quality Control

Our Aminooxy-Peg4-Azide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or oil
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.