Description

1-(Pyridin-4-Yl)Azetidin-3-Amine Dihydrochloride is a high-purity, advanced pharmaceutical intermediate and building block. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel small-molecule therapeutics. It is primarily utilized by pharmaceutical R&D teams, contract research organizations (CROs), and fine chemical manufacturers focused on developing new drug candidates, especially in areas like kinase inhibitors and central nervous system (CNS) agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs) for preclinical and clinical development.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Kinase Inhibitor Development: Serves as a core scaffold or precursor in the design of potential kinase-targeting therapeutics.
• CNS Drug Discovery: Employed in the research of compounds targeting neurological and psychiatric disorders.
• Chemical Biology Probes: Utilized to create tool compounds for studying biological pathways and target validation.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	1-(Pyridin-4-Yl)Azetidin-3-Amine Dihydrochloride
CAS No.	2098025-88-6
Molecular Formula	C8H13N3 · 2HCl
Molecular Weight	240.13 g/mol (as dihydrochloride salt)
Synonyms	1-(4-Pyridyl)azetidin-3-amine dihydrochloride; 3-Amino-1-(4-pyridinyl)azetidine dihydrochloride; 1-(Pyridin-4-yl)azetidin-3-amine hydrochloride (1:2); Azetidin-3-amine, 1-(4-pyridinyl)-, dihydrochloride; 2098025-88-6; 1-(4-Pyridyl)-3-aminocyclobutane dihydrochloride (common name); 1-(Pyridin-4-Yl)Azetidin-3-Amine 2HCl
EINECS	Contact for details

Quality Control

Our 1-(Pyridin-4-Yl)Azetidin-3-Amine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to ensure traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.