Description

Cyanine5.5 Amine is a near-infrared fluorescent labeling reagent featuring a reactive primary amine group. This compound is essential for creating stable, bright conjugates for advanced bioimaging and diagnostic applications. It is primarily used by researchers and manufacturers in the fields of bioconjugation, in vivo imaging, and flow cytometry to develop highly sensitive probes and assays.

Application

• Bioconjugation and Probe Development: Labeling of antibodies, proteins, peptides, and oligonucleotides for fluorescence-based detection.
• In Vivo Imaging: Synthesis of targeted imaging agents for deep-tissue fluorescence microscopy and small animal imaging due to its near-infrared emission.
• Flow Cytometry: Preparation of fluorescent markers for cell sorting and analysis.
• Diagnostic Assays: Development of fluorescent lateral flow assays (LFAs) and ELISA kits.
• Nanoparticle Functionalization: Conjugation to quantum dots, liposomes, or polymer nanoparticles for theranostic applications.
• Drug Delivery Tracking: Labeling of drug carriers to monitor biodistribution and pharmacokinetics.

Basic Information

Product Name	Cyanine5.5 Amine
CAS No.	2097714-45-7
Molecular Formula	C40H49N3O2S2+ • X-
Molecular Weight	Contact for details
Synonyms	Cy5.5 Amine; Cy™5.5 Amine; Sulfo-Cyanine5.5 amine; Cyanine 5.5 NHS ester precursor; 1-(5-Carboxypentyl)-2-((1E,3E)-5-(1-(5-carboxypentyl)-3,3-dimethyl-5-sulfoindolin-2-ylidene)penta-1,3-dien-1-yl)-3,3-dimethyl-3H-indol-1-ium-5-sulfonate amine derivative; NIR dye amine; Near-infrared fluorescent amine
EINECS	Contact for details

Quality Control

Our Cyanine5.5 Amine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and spectrophotometry for absorbance and fluorescence verification. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	Dark green to blue solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Absorption Maximum (λmax)	~675 - 685 nm
Emission Maximum (λem)	~695 - 705 nm
Extinction Coefficient (ε)	≥ 190,000 cm-1M-1
Moisture Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.