Description

Ms-Peg8-T-Butyl Ester CAS NO 2097604-01-6 is a high-purity, functionalized polyethylene glycol (PEG) derivative featuring a terminal tert-butyl ester group. This compound is a critical intermediate and building block in advanced organic synthesis, particularly for the development of pharmaceuticals, bioconjugates, and specialty polymers. It is primarily utilized by research institutions, pharmaceutical developers, and fine chemical manufacturers requiring precise chemical modifications and controlled release systems.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of prodrugs, drug-linkers, and targeted therapeutic agents.
• Bioconjugation Chemistry: Used to modify peptides, proteins, and antibodies to enhance solubility, stability, and pharmacokinetic properties.
• Polymer Synthesis: Serves as a functional monomer or initiator for creating PEG-based hydrogels, smart materials, and drug delivery vehicles.
• Protecting Group Strategy: The tert-butyl ester moiety acts as a protecting group for carboxylic acids in multi-step synthetic routes.
• Surface Modification: Applied in the functionalization of nanoparticles and biomedical device surfaces to improve biocompatibility.
• Research & Development: Essential tool compound in academic and industrial R&D for exploring new chemical entities and formulations.

Basic Information

Product Name	Ms-Peg8-T-Butyl Ester
CAS No.	2097604-01-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Methanesulfonyl-PEG8-t-butyl ester; MS-PEG8-OtBu; α-Methanesulfonyl-ω-tert-butoxy-poly(ethylene glycol); PEG8 ditosylate tert-butyl ester derivative; 2,5,8,11,14,17,20,23-Octaoxapentacosane-1,25-dioic acid, 25-(1,1-dimethylethyl) ester, 1-methanesulfonate; tert-Butyl PEG8 mesylate; Poly(ethylene glycol) derivative with mesylate and t-butyl ester termini; 8-arm PEG tert-butyl ester mesylate
EINECS	Contact for details

Quality Control

Our Ms-Peg8-T-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specification results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.