Description

Methyl 8-Methoxy-1,4-Dioxaspiro[4.5]Decane-8-Carboxylate is a high-value, multifunctional spirocyclic building block and chiral synthon used in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific stereochemistry and functional complexity into their target molecules.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex drug candidates, particularly those requiring spirocyclic or bridged ring systems.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where specific stereochemistry impacts biological activity.
• Asymmetric Catalysis Substrate: Serves as a sophisticated substrate for testing and developing new chiral catalysts and methodologies.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals, including flavors, fragrances, and advanced materials.
• Academic & Industrial R&D: A valuable tool for synthetic organic chemists in universities and corporate labs exploring new reaction pathways and molecular design.
• Ligand and Catalyst Development: The structure can be modified to create novel chiral ligands for metal-catalyzed asymmetric transformations.

Basic Information

Product Name	Methyl 8-Methoxy-1,4-Dioxaspiro[4.5]Decane-8-Carboxylate
CAS No.	2097133-36-1
Molecular Formula	C12H20O5
Molecular Weight	244.28 g/mol
Synonyms	8-Methoxy-1,4-dioxaspiro[4.5]decane-8-carboxylic acid methyl ester; Methyl 8-methoxy-1,4-dioxaspiro[4.5]decane-8-carboxylate; 1,4-Dioxaspiro[4.5]decane-8-carboxylic acid, 8-methoxy-, methyl ester; Spirocyclic methyl ester; Methoxy dioxaspirodecane carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 8-Methoxy-1,4-Dioxaspiro[4.5]Decane-8-Carboxylate is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, critical for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. For projects requiring specific regulatory documentation, we can support with additional data packages upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.