Description

5-Iodo-2-(2-Methyl-2H-Tetrazol-5-Yl)Pyridine is a specialized heterocyclic building block of significant interest in modern pharmaceutical and agrochemical research. Its core value lies in the strategic combination of a pyridine scaffold with a tetrazole ring and an iodine substituent, making it a versatile intermediate for constructing complex molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical industry for applications such as medicinal chemistry and the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in kinase inhibitor programs and other small-molecule therapeutics.
• Medicinal Chemistry: Used for structure-activity relationship (SAR) studies and lead optimization due to its modifiable iodine handle and heterocyclic core.
• Agrochemical Research: Serves as a building block in the synthesis of new pesticides and herbicides, leveraging its bioactive heterocyclic structure.
• Chemical Biology: Employed in the synthesis of probes and ligands for studying biological targets and pathways.
• Material Science: Potential precursor for the development of advanced organic electronic materials or metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create diverse biaryl and conjugated systems.

Basic Information

Product Name	5-Iodo-2-(2-Methyl-2H-Tetrazol-5-Yl)Pyridine
CAS No.	2095840-86-9
Molecular Formula	C7H6IN5
Molecular Weight	287.06 g/mol
Synonyms	5-Iodo-2-(2-methyl-2H-tetrazol-5-yl)pyridine; 2-(2-Methyl-2H-tetrazol-5-yl)-5-iodopyridine; 5-Iodo-2-(2-methyltetrazol-5-yl)pyridine; 5-Iodo-2-(2-methyl-1,2,3,4-tetrazol-5-yl)pyridine; Pyridine, 5-iodo-2-(2-methyl-2H-tetrazol-5-yl)-; 2095840-86-9; 5-Iodo-2-(2-methyltetrazol-5-yl)pyridine
EINECS	Contact for details

Quality Control

Our 5-Iodo-2-(2-Methyl-2H-Tetrazol-5-Yl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP and ICH Q7 guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.