Description

n-(Azido-Peg4)-n-Boc-Peg3-T-Butyl Ester is a heterobifunctional polyethylene glycol (PEG) linker featuring an azide group and a tert-butyl ester-protected carboxylic acid, separated by Boc-protected amine and PEG spacers. This compound is engineered for highly efficient and selective conjugation in advanced bioconjugation and materials science applications, enabling the construction of complex molecular architectures. It is primarily utilized by researchers and manufacturers in pharmaceutical development, proteomics, and nanotechnology for creating stable, well-defined conjugates.

Application

• Bioconjugation and ADC Development: Key building block for site-specific conjugation of payloads (e.g., drugs, toxins, dyes) to antibodies, proteins, or peptides via copper-free click chemistry.
• Proteomics Research: Used for labeling and cross-linking biomolecules to study protein-protein interactions, structure, and function.
• Polymer and Materials Science: Serves as a functional linker for synthesizing PEGylated hydrogels, smart materials, and surface coatings with tailored properties.
• Diagnostic Reagent Synthesis: Facilitates the production of stable, water-soluble diagnostic probes and imaging agents.
• Drug Delivery Systems: Incorporated into the design of prodrugs and nanocarriers to improve solubility, pharmacokinetics, and targeted delivery.
• Chemical Biology Tool Development: Enables the creation of activity-based probes and other tools for exploring biological pathways.

Basic Information

Product Name	n-(Azido-Peg4)-n-Boc-Peg3-T-Butyl Ester
CAS No.	2093152-85-1
Molecular Formula	C33H64N4O13
Molecular Weight	724.88 g/mol
Synonyms	Azido-PEG4-Boc-PEG3-T-Butyl Ester; 1-Azido-3,6,9,12-tetraoxapentadecan-15-oic acid, 15-[(1,1-dimethylethoxy)carbonyl]-3,6,9,12-tetraoxa-15-azaoctadec-1-yl ester; Boc-N-amido-PEG3-PEG4-azide; t-Butyl ester-PEG3-Boc-NH-PEG4-azide; Azido-PEG4-N-Boc-PEG3-acid t-butyl ester; Heterobifunctional PEG linker, Azide/Boc-Amine/t-Butyl Ester; 2093152-85-1; Azido-PEG4-Boc-PEG3-COOtBu
EINECS	Contact for details

Quality Control

Our n-(Azido-Peg4)-n-Boc-Peg3-T-Butyl Ester is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity for research and development. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) with detailed specifications are provided to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store the product at -20°C or below under desiccant. The material is moisture-sensitive; allow the vial to equilibrate to room temperature in a dry environment before opening to prevent condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.