Description

Ethyl 8-Bromo-1,6-Naphthyridine-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate crucial for modern drug discovery and development. This compound serves as a versatile building block for synthesizing novel, biologically active molecules, particularly in the fields of oncology and antiviral research. It is essential for research chemists and process development scientists in pharmaceutical, biotechnology, and fine chemical industries seeking to create new therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Oncology Drug Development: Employed in the construction of kinase inhibitors and other targeted cancer therapies due to the naphthyridine core's affinity for binding pockets.
• Antiviral Agent Synthesis: Utilized in the research and development of novel antiviral compounds.
• Chemical Biology Probes: Acts as a starting material for creating molecular probes to study biological processes and identify new drug targets.
• Fine Chemical Synthesis: Serves as a specialized reagent for constructing complex heterocyclic systems in custom synthesis and contract manufacturing.

Basic Information

Product Name	Ethyl 8-Bromo-1,6-Naphthyridine-3-Carboxylate
CAS No.	2089652-13-9
Molecular Formula	C11H9BrN2O2
Molecular Weight	281.11 g/mol
Synonyms	8-Bromo-1,6-naphthyridine-3-carboxylic acid ethyl ester; Ethyl 8-bromo-1,6-naphthyridine-3-carboxylate; 1,6-Naphthyridine-3-carboxylic acid, 8-bromo-, ethyl ester; 2089652-13-9; 8-Bromo-1,6-naphthyridine-3-carboxylate ethyl ester; Ethyl 8-bromonaphthyridine-3-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 8-Bromo-1,6-Naphthyridine-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.