Description

Ethyl 8-Amino-1,6-naphthyridine-3-carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its naphthyridine core structure. This compound is critical for medicinal chemistry research and development, serving as a key building block in the synthesis of novel therapeutic agents. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new drug candidates, particularly in areas targeting specific enzymatic pathways.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) with potential kinase inhibitory activity.
• Medicinal Chemistry Research: Used as a scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Biochemical Tool Compound: Serves as a reference standard or a starting material for developing probes to study biological targets in academic and industrial research.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing specialized, high-value chemical entities.
• Agrochemical Research: Potential application as an intermediate in the development of new agrochemicals due to its heterocyclic structure.

Basic Information

Product Name	Ethyl 8-Amino-1,6-naphthyridine-3-carboxylate
CAS No.	2089651-29-4
Molecular Formula	C11H11N3O2
Molecular Weight	217.23 g/mol
Synonyms	Ethyl 8-amino-1,6-naphthyridine-3-carboxylate; 8-Amino-1,6-naphthyridine-3-carboxylic acid ethyl ester; 1,6-Naphthyridine-3-carboxylic acid, 8-amino-, ethyl ester; 2089651-29-4; Ethyl 8-amino-1,6-naphthyridine-3-carboxylate; 3-Carbethoxy-8-amino-1,6-naphthyridine
EINECS	Contact for details

Quality Control

Our Ethyl 8-Amino-1,6-naphthyridine-3-carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.