Description

Spiro[Piperidine-4,7'-[7H]Thieno[2,3-C]Pyran]-1,2'-Dicarboxylic Acid, 4',5'-Dihydro-5'-Methyl-, 1-(1,1-Dimethylethyl) Ester is a high-purity, advanced pharmaceutical intermediate characterized by its complex spirocyclic and heterocyclic architecture. This compound is of significant value in modern organic synthesis, serving as a critical building block for the development of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the discovery and scale-up of new drug candidates, particularly in areas requiring sophisticated molecular scaffolds.

Application

This specialized intermediate is designed for high-value synthetic applications, primarily within the life sciences sector.

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of potential drug candidates.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• API Development: Incorporated into the synthetic route for novel Active Pharmaceutical Ingredients, particularly those targeting central nervous system or metabolic disorders.
• Chemical Biology Probes: Utilized in the creation of specialized molecular tools for studying biological pathways and target validation.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule assembly.

Basic Information

Item	Details
Product Name	Spiro[Piperidine-4,7'-[7H]Thieno[2,3-C]Pyran]-1,2'-Dicarboxylic Acid, 4',5'-Dihydro-5'-Methyl-, 1-(1,1-Dimethylethyl) Ester
CAS No.	2088333-65-5
Molecular Formula	C19H25NO4S
Molecular Weight	363.47 g/mol
Synonyms	tert-Butyl 4',5'-dihydro-5'-methylspiro[piperidine-4,7'-[7H]thieno[2,3-c]pyran]-1,2'-dicarboxylate; 1-(tert-Butyl) 2'-methyl 4',5'-dihydro-5'-methylspiro[piperidine-4,7'-[7H]thieno[2,3-c]pyran]-1,2'-dicarboxylate; Spiro[piperidine-4,7'-[7H]thieno[2,3-c]pyran]-1,2'-dicarboxylic acid, 4',5'-dihydro-5'-methyl-, 1-(1,1-dimethylethyl) ester; CAS 2088333-65-5
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and high purity. Quality is verified through a comprehensive suite of analytical techniques including HPLC, GC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. We support development and cGMP-grade requirements, with specifications tailored to your project phase.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.