Description

Hydroxy-Peg3-Methyl Ester CAS NO 2086688-97-1 is a high-purity polyethylene glycol (PEG) derivative featuring a terminal hydroxyl group and a methyl ester. This bifunctional compound is a versatile building block in organic synthesis and bioconjugation, valued for its ability to introduce hydrophilic PEG spacers and serve as a reactive handle for further functionalization. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for applications such as linker synthesis, prodrug development, and polymer modification.

Application

• Pharmaceutical Linker Synthesis: Serves as a crucial intermediate for creating cleavable or non-cleavable linkers in antibody-drug conjugates (ADCs) and other targeted therapeutics.
• Prodrug Development: Used to modify drug molecules, enhancing their solubility, bioavailability, and pharmacokinetic properties through PEGylation.
• Bioconjugation Reagent: Acts as a spacer arm for attaching labels, probes, or other molecules to proteins, peptides, and surfaces without significantly altering their biological activity.
• Polymer Chemistry: Functions as a monomer or chain extender in the synthesis of specialized PEG-based copolymers and hydrogels for biomedical applications.
• Surface Modification: Employed to create hydrophilic, protein-resistant coatings on various materials for diagnostic and implantable devices.
• Crosslinking Agent: Utilized in the formation of biodegradable or stimuli-responsive networks in advanced material science.

Basic Information

Product Name	Hydroxy-Peg3-Methyl Ester
CAS No.	2086688-97-1
Molecular Formula	C10H20O6
Molecular Weight	236.26 g/mol
Synonyms	3,6,9-Trioxaundecanedioic acid, 11-hydroxy-, 1-methyl ester; 11-Hydroxy-3,6,9-trioxaundecanoic acid methyl ester; Methyl 11-hydroxy-3,6,9-trioxaundecanoate; HO-PEG3-CH2COOMe; Hydroxy-PEG3-acetic acid methyl ester; 2-[2-[2-(2-Hydroxyethoxy)ethoxy]ethoxy]acetic acid methyl ester; PEG3 methyl ester alcohol
EINECS	Contact for details

Quality Control

Our Hydroxy-Peg3-Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, assay, and impurity profiles. Our quality commitment supports applications in GMP and research environments where reliable specification and traceability are critical.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive). Allow the container to reach room temperature before opening to minimize moisture absorption. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.