Description

(3R,6S)-Methyl 6-Methylpiperidine-3-Carboxylate (2R,3R)-2,3-Dihydroxysuccinate is a high-purity chiral intermediate of significant importance in modern asymmetric synthesis. This compound is valued for its defined stereochemistry, which is critical for imparting specific biological activity and physical properties to the final target molecules. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular configurations.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex drug candidates, especially in central nervous system (CNS) and antiviral research.
• Asymmetric Catalysis: Used as a precursor or ligand in the development of chiral catalysts for enantioselective reactions.
• Agrochemical Research: Serves as a starting material for creating novel, stereochemically-defined pesticides and herbicides.
• Academic & R&D: Employed in university and corporate laboratories for methodological studies in organic and medicinal chemistry.
• Fine Chemical Synthesis: Integral to the production of other high-value, specialty chemicals where stereochemical purity is paramount.

Basic Information

Product Name	(3R,6S)-Methyl 6-Methylpiperidine-3-Carboxylate (2R,3R)-2,3-Dihydroxysuccinate
CAS No.	2070009-48-0
Molecular Formula	C12H21NO7
Molecular Weight	291.30 g/mol
Synonyms	(3R,6S)-Methyl 6-methylpiperidine-3-carboxylate (2R,3R)-2,3-dihydroxybutanedioate; Methyl (3R,6S)-6-methylpiperidine-3-carboxylate (2R,3R)-tartrate; (3R,6S)-6-Methylpiperidine-3-carboxylic acid methyl ester (2R,3R)-2,3-dihydroxysuccinate; L-(-)-Tartaric acid salt of Methyl (3R,6S)-6-methylnipecotate; Methyl (3R,6S)-6-methyl-3-piperidinecarboxylate (2R,3R)-2,3-dihydroxysuccinate (1:1); Chiral piperidine carboxylate tartrate salt
EINECS	Contact for details

Quality Control

Our production of (3R,6S)-Methyl 6-Methylpiperidine-3-Carboxylate (2R,3R)-2,3-Dihydroxysuccinate adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the exacting standards required for pharmaceutical R&D and cGMP manufacturing. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.