Description

3-Bromo-2-Methylphenylboronic Acid Pinacol Ester is a high-purity, synthetically valuable organoboron building block. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for constructing complex biaryl and heterobiaryl structures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing substituted biphenyl scaffolds.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides through palladium-catalyzed coupling reactions.
• Material Science: Serves as a precursor for creating advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Ligand & Catalyst Development: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology & Diagnostics: Useful for labeling and modifying biomolecules in probe and sensor development.
• Academic & Contract Research: A reliable reagent for methodological studies and custom synthesis projects in university and CRO laboratories.

Basic Information

Product Name	3-Bromo-2-Methylphenylboronic Acid Pinacol Ester
CAS No.	2057523-47-2
Molecular Formula	C13H18BBrO2
Molecular Weight	297.00 g/mol
Synonyms	2-Methyl-3-bromophenylboronic acid pinacol ester; (3-Bromo-2-methylphenyl)boronic acid pinacol ester; 4,4,5,5-Tetramethyl-2-(3-bromo-2-methylphenyl)-1,3,2-dioxaborolane; 3-Bromo-2-methylbenzeneboronic acid pinacol ester; Pinacol (3-bromo-2-methylphenyl)boronate; Boronic acid, B-(3-bromo-2-methylphenyl)-, 1,1-dimethylethyl ester (9CI)
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-2-Methylphenylboronic Acid Pinacol Ester is manufactured and tested under strict quality management systems. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles to ensure the material meets the exacting standards required for advanced synthetic applications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.