Description

5-Bromo-1,8-Naphthyridin-2-Amine is a high-purity, halogenated naphthyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel pharmaceuticals and agrochemicals, particularly in constructing complex heterocyclic cores. Research and development laboratories in the pharmaceutical, agrochemical, and material science industries need this specialized chemical for creating new active ingredients and functional molecules. Its precise structure offers unique reactivity for cross-coupling and functionalization reactions.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, especially kinase inhibitors and other biologically active small molecules.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides by acting as a core scaffold.
• Material Science: Serves as a building block for organic semiconductors, ligands for metal-organic frameworks (MOFs), and other functional organic materials.
• Chemical Synthesis: Utilized in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce complex amine and aryl functionalities.
• Academic & Contract Research: Essential for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO settings.

Basic Information

Product Name	5-Bromo-1,8-Naphthyridin-2-Amine
CAS No.	2056916-57-3
Molecular Formula	C8H6BrN3
Molecular Weight	224.06 g/mol
Synonyms	2-Amino-5-bromo-1,8-naphthyridine; 5-Bromo-1,8-naphthyridin-2-amine; 5-Bromo-2-amino-1,8-naphthyridine; 1,8-Naphthyridine, 5-bromo-2-amino-; 2056916-57-3; 5-Bromonaphthyridin-2-amine
EINECS	Contact for details

Quality Control

Our 5-Bromo-1,8-Naphthyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and may require storage under an inert atmosphere for long-term preservation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.