Description

Ethyl trans-4-Cyclopropylpyrrolidine-3-Carboxylate Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique cyclopropyl-pyrrolidine scaffold. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for synthesizing novel bioactive molecules. It is primarily sought after by pharmaceutical companies, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new therapeutic agents, particularly within central nervous system (CNS) and antiviral research domains.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of potential drug candidates.
• Medicinal Chemistry R&D: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Protease Inhibitor Synthesis: Serves as a precursor in the development of inhibitors targeting specific enzymes.
• Ligand and Scaffold Development: Utilized for creating novel chemical libraries and molecular scaffolds for high-throughput screening.
• Academic Research: Employed in university and institutional labs for studying heterocyclic chemistry and reaction mechanisms.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) producing bespoke compounds for clients.

Basic Information

Item	Details
Product Name	Ethyl trans-4-Cyclopropylpyrrolidine-3-Carboxylate Hydrochloride
CAS No.	2055840-84-9
Molecular Formula	C11H20ClNO2
Molecular Weight	233.74 g/mol
Synonyms	Ethyl (3R,4R)-4-Cyclopropylpyrrolidine-3-carboxylate Hydrochloride; trans-Ethyl 4-Cyclopropyl-3-pyrrolidinecarboxylate Hydrochloride; 4-Cyclopropyl-3-pyrrolidinecarboxylic Acid Ethyl Ester Hydrochloride; (3R,4R)-1-(Ethoxycarbonyl)-4-cyclopropylpyrrolidin-3-one Hydrochloride (tautomer); UNII-Contact for details; Pyrrolidine-3-carboxylic acid, 4-cyclopropyl-, ethyl ester, hydrochloride, (3R,4R)-; (3R,4R)-4-Cyclopropylpyrrolidine-3-carboxylic acid ethyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our Ethyl trans-4-Cyclopropylpyrrolidine-3-Carboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral purity analysis, and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions (e.g., nitrogen atmosphere) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.