Description

2H-Isoindole-2-Carboxylic Acid, 6-Bromo-1,3-Dihydro-1,1-Dimethyl-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its specific brominated isoindole core structure. This compound is of significant value for enabling complex synthetic routes in medicinal chemistry, particularly for the development of novel active pharmaceutical ingredients (APIs). It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate functionalized heterocyclic scaffolds into their target molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Agrochemical Synthesis: Serves as a precursor for developing novel herbicides or fungicides with unique modes of action.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories for constructing functionalized isoindole derivatives and other N-heterocycles.
• Chemical Biology Probes: Can be utilized to create molecular probes for studying biological processes and protein interactions.

Basic Information

Product Name	2H-Isoindole-2-Carboxylic Acid, 6-Bromo-1,3-Dihydro-1,1-Dimethyl-, 1,1-Dimethylethyl Ester
CAS No.	2055840-81-6
Molecular Formula	C15H18BrNO2
Molecular Weight	324.21 g/mol
Synonyms	tert-Butyl 6-bromo-1,1-dimethyl-2,3-dihydro-1H-isoindole-2-carboxylate; 6-Bromo-1,1-dimethyl-2,3-dihydro-1H-isoindole-2-carboxylic acid tert-butyl ester; 1,1-Dimethylethyl 6-bromo-1,3-dihydro-1,1-dimethyl-2H-isoindole-2-carboxylate; 2H-Isoindole-2-carboxylic acid, 6-bromo-1,3-dihydro-1,1-dimethyl-, 1,1-dimethylethyl ester; 2055840-81-6; tert-Butyl 6-bromo-1,1-dimethylisoindoline-2-carboxylate
EINECS	Contact for details

Quality Control

Our 2H-Isoindole-2-Carboxylic Acid, 6-Bromo-1,3-Dihydro-1,1-Dimethyl-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical R&D. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.