Description

Pc-Biotin-Peg4-Peg3-Azide CAS NO 2055198-04-2 is a high-purity, multifunctional chemical reagent designed for advanced bioconjugation and click chemistry applications. This compound integrates a biotin affinity tag with a flexible polyethylene glycol (PEG) spacer and a terminal azide group, enabling precise and efficient labeling of biomolecules. It is essential for researchers and manufacturers in the fields of proteomics, drug discovery, and diagnostic assay development who require reliable, site-specific modification of proteins, antibodies, and other biological entities.

Application

• ADC (Antibody-Drug Conjugate) Development: Site-specific conjugation of cytotoxic payloads to antibodies via strain-promoted azide-alkyne cycloaddition (SPAAC).
• Proteomics & Biomarker Discovery: Biotinylation of proteins or peptides for subsequent capture and analysis using streptavidin-based purification systems.
• Diagnostic Reagent Manufacturing: Labeling of detection antibodies or antigens in ELISA, lateral flow assays, and other immunoassays.
• Cell Surface Engineering: Modification of cell membranes with biotin tags for imaging, sorting, or therapeutic targeting applications.
• Polymer & Material Science: Functionalization of nanoparticles, hydrogels, and other polymeric materials with bioactive ligands.
• Small Molecule Prodrug Synthesis: Creating biotinylated prodrugs for targeted delivery and activation strategies.

Basic Information

Product Name	Pc-Biotin-Peg4-Peg3-Azide
CAS No.	2055198-04-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Biotin-PEG4-PEG3-azide; Biotin-PEG7-Azide; PC Biotin PEG4 PEG3 N3; Biotin-PEG(4)-PEG(3)-N3; N-(Biotinoyl)-3,6,9,12,15,18,21-heptaoxatricosan-23-azide; Azido-PEG7-Biotin; Biotinylated PEG-azide; 23-Azido-3,6,9,12,15,18,21-heptaoxatricosan-1-amide of Biotin
EINECS	Contact for details

Quality Control

Our Pc-Biotin-Peg4-Peg3-Azide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry, to ensure it meets the high standards required for research and biopharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, moisture-free environment. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid or viscous oil
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF, Methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.