Description

n-Boc-n-Bis(Peg4-Azide) is a specialized bifunctional PEG-based linker molecule, featuring a Boc-protected amine and dual terminal azide groups. This compound is engineered to facilitate controlled, orthogonal bioconjugation and click chemistry reactions, enabling the precise construction of complex molecular architectures. It is essential for researchers and developers in pharmaceutical R&D, proteomics, and advanced materials science who require reliable, high-purity building blocks for drug delivery systems, diagnostic probes, and polymer modification.

Application

• Bioconjugation and Antibody-Drug Conjugate (ADC) Development: Serves as a heterobifunctional crosslinker for site-specific attachment of payloads to proteins or antibodies via copper-free click chemistry.
• Polymer and Dendrimer Synthesis: Acts as a key monomer or chain extender for creating functionalized, water-soluble PEG-based polymers with defined reactive sites.
• Surface Functionalization and Nanomaterial Labeling: Used to modify nanoparticles, quantum dots, or biosensor surfaces with azide groups for subsequent bio-orthogonal ligation.
• Chemical Biology and Proteomics: Enables the synthesis of activity-based probes or affinity tags for studying protein function and interactions in living systems.
• Drug Delivery System Fabrication: Incorporated into micelles, liposomes, or hydrogels to create stimuli-responsive or targeted delivery platforms.
• Diagnostic Reagent Formulation: Utilized in the development of advanced immunoassays and molecular imaging agents.

Basic Information

Product Name	n-Boc-n-Bis(Peg4-Azide)
CAS No.	2055041-25-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	1-Boc-1,1-bis[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethyl]amine; tert-Butyl bis(2,5,8,11-tetraoxatridecan-13-yl-azide)carbamate; Boc-NH-PEG4-azide (branched); Bifunctional PEG4 Azide Linker; Boc-protected bis-PEG4-azide; 2055041-25-1; Azido-PEG4-t-butyloxycarbonylamino-PEG4-azide
EINECS	Contact for details

Quality Control

Our n-Boc-n-Bis(Peg4-Azide) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in research and pre-clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. The product is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep container tightly sealed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.