Description

Azide-Peg3-Sulfone-Peg3-Azide is a heterobifunctional polyethylene glycol (PEG) crosslinker featuring terminal azide groups and a central sulfone moiety. This compound is engineered for high-efficiency conjugation and bioconjugation applications, enabling the formation of stable linkages under mild conditions. It is a critical reagent for researchers and manufacturers in pharmaceutical development, proteomics, and advanced materials science, where precise and reliable molecular assembly is required.

Application

• Bioconjugation and Antibody-Drug Conjugate (ADC) Development: Used as a linker to connect cytotoxic drugs to monoclonal antibodies via click chemistry.
• Proteomics and Biomarker Discovery: Facilitates the labeling and crosslinking of proteins and peptides for analysis and purification.
• Polymer and Hydrogel Synthesis: Serves as a functional crosslinking agent to create PEG-based networks with tailored properties for drug delivery and tissue engineering.
• Surface Functionalization: Enables the modification of nanoparticles, biosensors, and diagnostic devices with bioactive molecules.
• Chemical Biology Tool Development: A key reagent for creating activity-based probes and other chemical tools to study biological processes.
• Materials Science: Used in the synthesis of functionalized polymers and smart materials with responsive characteristics.

Basic Information

Item	Detail
Product Name	Azide-Peg3-Sulfone-Peg3-Azide
CAS No.	2055024-45-6
Molecular Formula	C16H30N6O8S
Molecular Weight	466.51 g/mol
Synonyms	1,11-Bis(azido)-3,6,9-trioxaundecane-1-sulfone; PEG3-Sulfone-PEG3-diazide; Bis(azido-PEG3) sulfone; Azido-PEG3-Sulfone-PEG3-azide; Heterobifunctional PEG crosslinker, azide-sulfone-azide; 1-Azido-11-azido-3,6,9-trioxaundecane sulfone; N3-PEG3-SO2-PEG3-N3
EINECS	Contact for details

Quality Control

Our Azide-Peg3-Sulfone-Peg3-Azide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and cGMP manufacturing needs with documentation and regulatory support.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid or viscous liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.