Description

Azd-Peg5 -Methyl Ester is a high-purity, functionalized polyethylene glycol (PEG) derivative designed for advanced bioconjugation and linker chemistry. This compound is critical for researchers and manufacturers requiring precise, reproducible modification of biomolecules, peptides, and small molecule APIs. It is primarily utilized in the pharmaceutical and biotechnology sectors for drug discovery, development of antibody-drug conjugates (ADCs), and the synthesis of complex molecular probes.

Application

• Bioconjugation Linker: Serves as a versatile, hydrophilic spacer arm for conjugating targeting ligands (e.g., antibodies, peptides) to cytotoxic drugs, imaging agents, or other payloads.
• ADC (Antibody-Drug Conjugate) Development: A key intermediate in the synthesis of ADCs, where its PEG chain improves solubility and pharmacokinetic properties of the final conjugate.
• Proteolysis-Targeting Chimera (PROTAC) & Molecular Glues: Used as a component in bifunctional linker systems for targeted protein degradation platforms.
• Peptide & Protein Modification: Enables site-specific PEGylation to enhance stability, reduce immunogenicity, and prolong the half-life of therapeutic peptides and proteins.
• Diagnostic Reagent Synthesis: Employed in the creation of contrast agents and fluorescent probes for in vitro and in vivo imaging applications.
• Polymer Chemistry & Material Science: Acts as a functional monomer or cross-linker for synthesizing smart hydrogels and biocompatible polymers with tailored properties.

Basic Information

Product Name	Azd-Peg5 -Methyl Ester
CAS No.	2055014-59-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	2-[2-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethyl methyl succinate; Azido-PEG5-methyl ester; Methyl-PEG5-azide; Azido-PEG5-acid methyl ester; Azido-PEG5-OMe; 5-Azido-3,6,9,12,15-pentaoxaoctadecan-1-oic acid methyl ester; Azido-PEG5-methyl succinate; N3-PEG5-methyl ester
EINECS	Contact for details

Quality Control

Our Azd-Peg5 -Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation and under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or oil
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.