Description

3H-Spiro[Furo[3,4-C]Pyridine-1,4'-Piperidine] Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS number 2044706-82-1. This spirocyclic compound is a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold in drug discovery programs for structure-activity relationship (SAR) studies and lead optimization.
• Chemical Biology Probes: Serves as a core structure for developing tool compounds to study biological pathways and target validation.
• Process Development: Employed in route scouting and scale-up studies for the efficient manufacturing of complex drug molecules.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global pharmaceutical R&D pipelines.

Basic Information

Product Name	3H-Spiro[Furo[3,4-C]Pyridine-1,4'-Piperidine] Hydrochloride
CAS No.	2044706-82-1
Molecular Formula	C11H14ClN2O
Molecular Weight	225.70 g/mol
Synonyms	3H-Spiro[furo[3,4-c]pyridine-1,4'-piperidine] hydrochloride; 1',4'-Dihydrospiro[furo[3,4-c]pyridine-1,4'-piperidin]-3-one hydrochloride; Spiro[furo[3,4-c]pyridine-1,4'-piperidine] hydrochloride; 2044706-82-1; Furo[3,4-c]pyridine-1,4'-piperidine hydrochloride spiro derivative
EINECS	Contact for details

Quality Control

Our 3H-Spiro[Furo[3,4-C]Pyridine-1,4'-Piperidine] Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all relevant specifications. We support development and commercial projects requiring compliance with cGMP and ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity	≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.