Description

((2R,4R)-2-Methylpiperidin-4-Yl)Methanol Hydrochloride CAS NO 2044705-36-2 is a high-purity chiral piperidine derivative, specifically the hydrochloride salt of a substituted piperidinemethanol. This compound serves as a critical pharmaceutical intermediate and chiral building block in advanced organic synthesis. It is primarily required by research institutions and chemical manufacturers engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where stereochemical control is paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules, particularly those targeting the central nervous system.
• Asymmetric Catalysis: Used as a precursor for chiral ligands or catalysts in enantioselective synthesis.
• Agrochemical Research: Serves as a building block for novel pesticides and herbicides with specific stereochemical requirements.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and the discovery of new chemical entities.
• Chemical Biology: Utilized in the development of molecular probes and tool compounds for biological research.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke fine chemicals.

Basic Information

Product Name	((2R,4R)-2-Methylpiperidin-4-Yl)Methanol Hydrochloride
CAS No.	2044705-36-2
Molecular Formula	C7H16ClNO
Molecular Weight	165.66 g/mol
Synonyms	(2R,4R)-2-Methyl-4-piperidinemethanol hydrochloride; (2R,4R)-2-Methylpiperidine-4-methanol hydrochloride; 4-Piperidinemethanol, 2-methyl-, (2R,4R)-, hydrochloride; (2R,4R)-2-Methyl-4-(hydroxymethyl)piperidine hydrochloride; (2R,4R)-HMP hydrochloride; (2R,4R)-2-Methyl-4-piperidinylmethanol HCl; (2R,4R)-2-Methyl-4-(hydroxymethyl)piperidinium chloride
EINECS	Contact for details

Quality Control

Our production of ((2R,4R)-2-Methylpiperidin-4-Yl)Methanol Hydrochloride adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.