Description

Bdp Fl Methyltetrazine is a high-purity, functionalized tetrazine derivative designed for advanced bioconjugation and materials science applications. This compound is critical for researchers and manufacturers requiring a reliable, high-quality linker for bioorthogonal click chemistry, particularly in the development of targeted diagnostics and therapeutics. It is essential for professionals in pharmaceutical R&D, biotech, and advanced material synthesis who need precise and stable conjugation tools.

Application

• Bioorthogonal Labeling and Imaging: Used as a key reagent for inverse electron demand Diels-Alder (IEDDA) reactions to label biomolecules in live cells and tissues for fluorescence imaging.
• Antibody-Drug Conjugate (ADC) Development: Serves as a specialized linker for attaching cytotoxic payloads to monoclonal antibodies, enabling targeted cancer therapy.
• Pretargeted Radioimmunotherapy: Facilitates the multi-step targeting strategy for delivering radioactive isotopes to tumor sites with high specificity.
• Polymer and Surface Functionalization: Enables the modification of nanomaterials, hydrogels, and solid surfaces with bioactive molecules for sensor and device fabrication.
• Chemical Biology Probes: Integral for synthesizing activity-based probes to study enzyme function and protein interactions within complex biological systems.
• Diagnostic Assay Development: Employed in the construction of sensitive immunoassays and biosensors due to its fast and specific conjugation kinetics.

Basic Information

Product Name	Bdp Fl Methyltetrazine
CAS No.	2042193-77-9
Molecular Formula	C19H17BF2N6O2
Molecular Weight	422.20 g/mol
Synonyms	BDP FL methyltetrazine; BODIPY FL methyltetrazine; 4-((4-(4,4-Difluoro-5-(2-thienyl)-4-bora-3a,4a-diaza-s-indacene-3-yl)phenoxy)acetyl)amino)methyl)-1-methyl-1,2,4,5-tetrazine; Methyltetrazine-BDP FL; BDP FL-Tetrazine; BODIPY® FL Tetrazine; Tetrazine-BODIPY FL conjugate; Bdp-Fl-MeTz
EINECS	Contact for details

Quality Control

Every batch of Bdp Fl Methyltetrazine is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and performance. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliable and reproducible results for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and strictly light-sensitive (protect from all light exposure). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Red to dark red solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.