Description

m-Peg6-(Ch2)8-Phosphonic Acid is a specialized bifunctional organic compound that combines a hydrophilic polyethylene glycol (PEG) spacer with a terminal phosphonic acid group. This unique structure provides excellent water solubility and strong metal-chelating properties, making it a critical intermediate for advanced material science and bioconjugation. It is essential for researchers and manufacturers in the pharmaceutical, nanotechnology, and surface modification industries who require precise molecular design for drug delivery systems, diagnostic agents, and functional coatings.

Application

• Pharmaceutical Linker: Used as a key building block for creating water-soluble prodrugs and antibody-drug conjugates (ADCs) to improve therapeutic efficacy and reduce side effects.
• Surface Functionalization Agent: Employed to modify the surface of nanoparticles, quantum dots, and medical implants with a stable, hydrophilic, and bioactive phosphonate layer.
• Metal Chelation & Catalysis: Serves as a ligand for metal ions in catalytic systems or as a component in materials for metal sequestration and recovery processes.
• Bioconjugation & Diagnostics: Facilitates the stable attachment of biomolecules (peptides, proteins, oligonucleotides) to various substrates for diagnostic assays and biosensors.
• Polymer Modification: Incorporated into polymer backbones to introduce phosphonate functionality, enhancing properties like flame retardancy, adhesion to metal surfaces, or biocompatibility.
• Research Chemical: A valuable tool in academic and industrial R&D for exploring new materials, drug delivery platforms, and surface chemistry.

Basic Information

Product Name	m-Peg6-(Ch2)8-Phosphonic Acid
CAS No.	2028284-71-9
Molecular Formula	C22H47O10P
Molecular Weight	502.58 g/mol
Synonyms	8-[2-[2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]octylphosphonic acid; α-Methyl-ω-phosphonooctylhexaethylene glycol; mPEG6-C8-Phosphonic Acid; Hexaethylene glycol monomethyl ether C8-phosphonate; (8-{2-[2-(2-{2-[2-(2-Methoxy-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-octyl)-phosphonic acid; HO-PEG6-C8-PO3H2; mPEG6(C8)phosphonic acid
EINECS	Contact for details

Quality Control

Our m-Peg6-(Ch2)8-Phosphonic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial applications. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request. We support compliance with relevant guidelines for use in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This material is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Phosphonic Acid Content	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.