Description

m-Peg6-(Ch2)8-Phosphonic Acid Ethyl Ester is a specialized bifunctional organic compound featuring a hydrophilic polyethylene glycol (PEG) spacer linked to a phosphonic acid ethyl ester moiety. This unique structure makes it a valuable intermediate for introducing hydrophilic, non-fouling properties and stable metal-binding or surface-modifying functionalities. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for applications such as bioconjugation, surface functionalization, and the development of novel drug delivery systems.

Application

• Bioconjugation Linker: Used to modify peptides, proteins, or antibodies with PEG chains to improve solubility, stability, and pharmacokinetics.
• Surface Functionalization Agent: Applied to coat metal oxides (e.g., titanium, iron oxide) or glass surfaces to create hydrophilic, anti-fouling, or specific binding layers.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of targeted drug conjugates and prodrugs.
• Material Science: Employed in the development of hydrogels, smart polymers, and nanocomposites requiring specific metal-chelation or surface properties.
• Diagnostic Reagents: Used in the formulation of contrast agents or biosensor surfaces where stable anchoring to inorganic materials is required.
• Catalyst and Ligand Synthesis: Acts as a precursor for creating novel ligands in coordination chemistry and catalysis.

Basic Information

Product Name	m-Peg6-(Ch2)8-Phosphonic Acid Ethyl Ester
CAS No.	2028281-88-9
Molecular Formula	C25H53O11P
Molecular Weight	560.66 g/mol
Synonyms	8-[2-[2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]octylphosphonic acid ethyl ester; Ethyl 8-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]octylphosphonate; mPEG6-C8-Phosphonate ethyl ester; (Ethoxyphosphoryl)-PEG6-C8; HO-PEG6-C8-P(O)(OEt)OH; Phosphonic acid, P-[8-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]octyl]-, ethyl ester
EINECS	Contact for details

Quality Control

Our m-Peg6-(Ch2)8-Phosphonic Acid Ethyl Ester is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive). Allow the container to reach room temperature before opening to minimize moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.