Description

Benzoic Acid, 3-Hydroxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-, Methyl Ester is a high-value, synthetically versatile boronic ester derivative of a substituted benzoic acid. This compound is a critical building block in modern organic synthesis, particularly for cross-coupling reactions that form carbon-carbon bonds. It is essential for research and development chemists in the pharmaceutical and agrochemical industries who require precise molecular construction for new active ingredients.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing biaryl and other complex aromatic structures in pharmaceutical intermediates.
• Pharmaceutical Research & Development: Serves as a versatile building block for synthesizing potential drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides with specific modes of action.
• Material Science: A precursor for creating organic electronic materials, such as those used in OLEDs and sensors.
• Chemical Biology & Proteomics: Employed in the synthesis of probes and inhibitors for studying enzyme function and protein interactions.
• Custom Synthesis & Contract Manufacturing: A valuable intermediate for companies offering bespoke chemical synthesis services.

Basic Information

Product Name	Benzoic Acid, 3-Hydroxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-, Methyl Ester
CAS No.	2026647-81-2
Molecular Formula	C15H21BO5
Molecular Weight	292.14 g/mol
Synonyms	Methyl 3-Hydroxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate; 4-Boronic acid, 3-hydroxy-, methyl ester, pinacol ester; Methyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-hydroxybenzoate; 3-Hydroxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid methyl ester; Pinacol ester of Methyl 3-hydroxy-4-boronobenzoate
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 3-Hydroxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (HPLC, Area%)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.