Description

tert-Butyl 2-(2-Methyl-1-Pyrrolidinyl)Acetate is a high-purity chemical intermediate featuring a pyrrolidine scaffold and a tert-butyl ester protecting group. This compound matters for its role as a versatile building block in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing active pharmaceutical ingredients (APIs) and other specialty compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the research and scale-up synthesis of novel drug candidates, particularly those targeting the central nervous system.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where the pyrrolidine moiety imparts specific biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and flavors/fragrances.
• Academic and R&D Laboratories: Utilized in methodological research and the discovery of new chemical reactions and pathways.
• Peptidomimetic Chemistry: The structure is valuable for creating peptide analogs and mimetics in medicinal chemistry programs.

Basic Information

Product Name	tert-Butyl 2-(2-Methyl-1-Pyrrolidinyl)Acetate
CAS No.	2015655-98-6
Molecular Formula	C11H21NO2
Molecular Weight	199.29 g/mol
Synonyms	2-(2-Methyl-1-pyrrolidinyl)acetic acid tert-butyl ester; 1-(tert-Butoxycarbonylmethyl)-2-methylpyrrolidine; tert-Butyl (2-methylpyrrolidin-1-yl)acetate; 2-Methyl-1-pyrrolidineacetic acid tert-butyl ester; Acetic acid, 2-(2-methyl-1-pyrrolidinyl)-, 1,1-dimethylethyl ester; t-Butyl 2-(2-methylpyrrolidin-1-yl)acetate
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-(2-Methyl-1-Pyrrolidinyl)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.