Description

tert-Butyl 5,5-Difluoro-2,7-Diazaspiro[3.5]Nonane-2-Carboxylate is a high-value, fluorinated spirocyclic building block designed for advanced pharmaceutical and agrochemical research. This compound matters because its unique diazaspiro[3.5]nonane core, combined with fluorine atoms, offers medicinal chemists a powerful tool for modulating the physicochemical properties, metabolic stability, and binding affinity of new drug candidates. It is primarily needed by R&D scientists in the pharmaceutical industry for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially those targeting protein-protein interactions and challenging biological targets.
• Medicinal Chemistry: Used in lead optimization to introduce conformational constraint and fluorine atoms, improving metabolic stability, lipophilicity, and membrane permeability of molecules.
• Agrochemical Research: Serves as a sophisticated scaffold in the development of new-generation pesticides and herbicides, leveraging the bioactivity of the diazaspiro structure.
• Chemical Biology Probe Development: Employed to create tool compounds for studying enzyme function and biological pathways due to its three-dimensional, shape-diverse architecture.
• Library Synthesis for High-Throughput Screening: Used to generate focused libraries of compounds for screening against novel biological targets in drug discovery campaigns.

Basic Information

Product Name	tert-Butyl 5,5-Difluoro-2,7-Diazaspiro[3.5]Nonane-2-Carboxylate
CAS No.	2007920-32-1
Molecular Formula	C12H20F2N2O2
Molecular Weight	262.30 g/mol
Synonyms	2,7-Diazaspiro[3.5]nonane-2-carboxylic acid, 5,5-difluoro-, 1,1-dimethylethyl ester; 5,5-Difluoro-2,7-diazaspiro[3.5]nonane-2-carboxylic acid tert-butyl ester; tert-Butyl 5,5-difluoro-2,7-diazaspiro[3.5]nonane-2-carboxylate; Boc-5,5-Difluoro-2,7-diazaspiro[3.5]nonane; 5,5-Difluoro-2,7-diazaspiro[3.5]nonane-2-Boc; 2007920-32-1; 2-Boc-5,5-difluoro-2,7-diazaspiro[3.5]nonane
EINECS	Contact for details

Quality Control

Our tert-Butyl 5,5-Difluoro-2,7-Diazaspiro[3.5]Nonane-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee traceability and batch-to-batch consistency, meeting the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.