Description

4-Nitro-3-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine is a high-value, multi-functional heterocyclic building block distinguished by its nitro and trifluoromethyl substituents. This compound is critical for research and development in advanced organic synthesis, where it serves as a versatile precursor for creating complex molecular architectures. It is primarily sought after by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, as well as by academic and industrial researchers in material science.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor research and other targeted therapies.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the bioactivity of the pyrrolopyridine core.
• Material Science Research: Serves as a building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-deficient character.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological processes and enzyme functions.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry, including cross-coupling and functional group transformation studies.

Basic Information

Product Name	4-Nitro-3-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine
CAS No.	2007917-56-6
Molecular Formula	C8H4F3N3O2
Molecular Weight	231.14 g/mol
Synonyms	4-Nitro-3-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 4-nitro-3-(trifluoromethyl)-; 3-(Trifluoromethyl)-4-nitro-1H-pyrrolo[2,3-b]pyridine; 4-Nitro-3-trifluoromethyl-1H-pyrrolo[2,3-b]pyridine; Pyrrolo[2,3-b]pyridine, 4-nitro-3-(trifluoromethyl)-1H-
EINECS	Contact for details

Quality Control

Our 4-Nitro-3-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our commitment to quality supports compliance with cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Yellow to light brown powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95% (Standard Grade)
Purity (HPLC)	≥ 98% (High Purity Grade)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.