Description

Benzyl 3-Oxo-1-Oxa-8-Azaspiro[4.5]Decane-8-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in neurological and psychiatric therapeutic areas. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of next-generation central nervous system (CNS) drugs and other specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates, especially those targeting neurological receptors.
• Research & Development (R&D): Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new bioactive molecules.
• API Synthesis: Serves as a core scaffold for constructing active pharmaceutical ingredients with spirocyclic architectures.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the production of clinical trial materials and commercial APIs.
• Chemical Biology: Employed in the development of chemical probes to study biological pathways and protein functions.

Basic Information

Product Name	Benzyl 3-Oxo-1-Oxa-8-Azaspiro[4.5]Decane-8-Carboxylate
CAS No.	2001507-82-8
Molecular Formula	C17H21NO4
Molecular Weight	303.35 g/mol
Synonyms	8-Benzyloxycarbonyl-3-oxo-1-oxa-8-azaspiro[4.5]decane; 1-Oxa-8-azaspiro[4.5]decane-8-carboxylic acid, 3-oxo-, benzyl ester; Benzyl 8-azaspiro[4.5]decane-8-carboxylate-3-one-1-oxide; BOC-Protected Spirocyclic Lactone Intermediate; CAS 2001507-82-8
EINECS	Contact for details

Quality Control

Our Benzyl 3-Oxo-1-Oxa-8-Azaspiro[4.5]Decane-8-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere); therefore, containers should be kept sealed under an inert gas (e.g., nitrogen or argon) when not in use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.