Description

Methyl 2-([(4-Fluorophenyl)Sulfonyl]Oxy)-5-Iodobenzenecarboxylate is a high-purity, synthetic organic intermediate of significant importance in advanced pharmaceutical research and development. Its complex molecular architecture, featuring both sulfonyloxy and iodo substituents, makes it a valuable building block for constructing novel active pharmaceutical ingredients (APIs). This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for targeted synthesis programs, including the development of kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Research: Serves as a building block for developing new generation herbicides and fungicides with specific modes of action.
• Chemical Biology Probe Development: Used in medicinal chemistry to create molecular probes for studying enzyme function and biological pathways.
• Material Science Research: Potential monomer or cross-linking agent in the development of specialty polymers with unique electronic or optical properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to outsourcing partners for custom synthesis and scale-up projects under cGMP or research-grade conditions.
• Academic Research: Utilized in university and institutional labs for methodological studies in cross-coupling reactions and heterocyclic chemistry.

Basic Information

Product Name	Methyl 2-([(4-Fluorophenyl)Sulfonyl]Oxy)-5-Iodobenzenecarboxylate
CAS No.	297150-19-7
Molecular Formula	C14H10FIO5S
Molecular Weight	436.19 g/mol
Synonyms	Methyl 5-Iodo-2-[(4-fluorophenyl)sulfonyloxy]benzoate; 2-[(4-Fluorobenzenesulfonyl)oxy]-5-iodobenzoic Acid Methyl Ester; Benzoic acid, 5-iodo-2-[(4-fluorophenyl)sulfonyl]oxy]-, methyl ester; Methyl 5-iodosalicylate 2-(4-fluorobenzenesulfonate); 297150-19-7; Methyl 2-((4-fluorophenyl)sulfonyloxy)-5-iodobenzoate
EINECS	Contact for details

Quality Control

Our production of Methyl 2-([(4-Fluorophenyl)Sulfonyl]Oxy)-5-Iodobenzenecarboxylate adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for critical R&D applications. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment. We support development under quality frameworks suitable for pre-clinical and early-phase clinical manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.