Description

(S)-Ethyl 4-(tert-Butoxycarbonyl)-4-Phenylbutanoate is a high-value chiral intermediate characterized by its phenylbutanoate core and tert-butoxycarbonyl (Boc) protecting group. This compound is critical for ensuring enantiomeric purity in the synthesis of complex pharmaceutical molecules, particularly those targeting the central nervous system. It is primarily required by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of chiral drugs, especially in neurological and psychiatric therapeutic areas.
• Peptidomimetics Research: Used in the design and construction of peptide-like molecules for drug discovery programs.
• Asymmetric Synthesis: Serves as a chiral precursor in catalytic asymmetric reactions to create enantiomerically pure compounds.
• API Development: Integral in the research and scale-up phases of new Active Pharmaceutical Ingredient (API) manufacturing.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals for advanced material science.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic and medicinal chemistry laboratories.

Basic Information

Product Name	(S)-Ethyl 4-(tert-Butoxycarbonyl)-4-Phenylbutanoate
CAS No.	296778-55-7
Molecular Formula	C₁₇H₂₄O₄
Molecular Weight	292.37 g/mol
Synonyms	(S)-Ethyl 4-((tert-Butoxycarbonyl)amino)-4-phenylbutanoate; (S)-4-((tert-Butoxycarbonyl)amino)-4-phenylbutanoic Acid Ethyl Ester; Ethyl (3S)-3-[(tert-Butoxycarbonyl)amino]-3-phenylpropionate; (S)-Boc-4-Phenyl-4-aminobutanoic Acid Ethyl Ester; (S)-N-Boc-4-Phenyl-4-aminobutanoic Acid Ethyl Ester; (S)-Ethyl 4-(Boc-amino)-4-phenylbutyrate; Boc-Phe(4)-OEt; (S)-Ethyl 4-[(2-methylpropan-2-yl)oxycarbonyl]amino-4-phenylbutanoate
EINECS	Contact for details

Quality Control

Our (S)-Ethyl 4-(tert-Butoxycarbonyl)-4-Phenylbutanoate is manufactured under strict quality systems to ensure batch-to-batch consistency and high enantiomeric purity. Production adheres to cGMP guidelines where applicable, and each lot is supported by a comprehensive Certificate of Analysis (COA). The COA includes critical parameters such as chiral purity (HPLC), chemical purity, and residual solvent analysis, meeting the stringent requirements of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is sensitive to strong acids and organic solvents; keep away from incompatible materials. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.