Description

2-Morpholin-4-Yl-Isonicotinic Acid is a high-purity organic building block featuring a combined morpholine and isonicotinic acid scaffold. This compound is valued for its role as a critical intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides that require specific heterocyclic architectures for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for designing specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the synthesis of molecular probes for studying enzyme function and biological pathways.
• Material Science Research: Acts as a building block for organic semiconductors, polymers, and other functional materials requiring conjugated systems with nitrogen heterocycles.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects at various scales.

Basic Information

Product Name	2-Morpholin-4-Yl-Isonicotinic Acid
CAS No.	295349-64-3
Molecular Formula	C10H12N2O3
Molecular Weight	208.22 g/mol
Synonyms	2-(Morpholin-4-yl)isonicotinic acid; 4-Pyridinecarboxylic acid, 2-(4-morpholinyl)-; 2-Morpholinoisonicotinic acid; 2-(4-Morpholinyl)isonicotinic acid; 295349-64-3; Isonicotinic acid, 2-morpholino-; AKOS005258212; BDBM50389335; ZINC000003870756
EINECS	Contact for details

Quality Control

Our 2-Morpholin-4-Yl-Isonicotinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.