Description

2-(4-Morpholinyl)-Pyridine-4-Carboxylic Acid tert-Butyl Ester is a high-purity, protected carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. Its molecular architecture, featuring both a morpholine and a pyridine ring, makes it a versatile intermediate for constructing complex pharmacologically active molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic structure.
• Ligand Synthesis: Serves as a starting material for creating complex chelating ligands used in catalysis and material science.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A valuable intermediate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic & Institutional Research: Used in university and institutional labs for methodological development and exploring new chemical spaces.

Basic Information

Product Name	2-(4-Morpholinyl)-Pyridine-4-Carboxylic Acid tert-Butyl Ester
CAS No.	295349-63-2
Molecular Formula	C14H20N2O3
Molecular Weight	264.32 g/mol
Synonyms	tert-Butyl 2-(morpholin-4-yl)pyridine-4-carboxylate; 4-Pyridinecarboxylic acid, 2-(4-morpholinyl)-, 1,1-dimethylethyl ester; 2-Morpholin-4-yl-pyridine-4-carboxylic acid tert-butyl ester; 2-(N-Morpholino)isonicotinic acid tert-butyl ester; 2-(4-Morpholinyl)isonicotinic acid tert-butyl ester; tert-Butyl 2-morpholinopyridine-4-carboxylate; CAS 295349-63-2
EINECS	Contact for details

Quality Control

Our 2-(4-Morpholinyl)-Pyridine-4-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.