Description

2-Chloropyridine-4-Carboxylic Acid tert-Butyl Ester is a high-purity, versatile pyridine derivative serving as a critical building block in advanced organic synthesis. Its value lies in the strategic combination of a reactive chloropyridine core with a protected carboxylic acid group, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly for active pharmaceutical ingredients (APIs) targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the pyridine scaffold is a common bioactive motif.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials that incorporate heterocyclic units.
• Custom Chemical Synthesis: Provides a versatile handle for medicinal chemistry and process R&D teams for structure-activity relationship (SAR) studies and lead optimization.

Basic Information

Item	Details
Product Name	2-Chloropyridine-4-Carboxylic Acid tert-Butyl Ester
CAS No.	295349-62-1
Molecular Formula	C10H12ClNO2
Molecular Weight	213.66 g/mol
Synonyms	tert-Butyl 2-chloropyridine-4-carboxylate; 2-Chloroisonicotinic Acid tert-Butyl Ester; 4-(tert-Butoxycarbonyl)-2-chloropyridine; 2-Chloro-4-pyridinecarboxylic Acid 1,1-Dimethylethyl Ester; 2-Chloro-4-(tert-butoxycarbonyl)pyridine; 2-Chloroisonicotinic Acid 1,1-Dimethylethyl Ester; 2-Chloro-4-pyridinecarboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 2-Chloropyridine-4-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.