Description

1-tert-Butyl 4-(Pentafluorophenyl) Piperidine-1,4-Dicarboxylate is a high-value, multi-functional piperidine derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in the unique reactivity imparted by the pentafluorophenyl and tert-butyl carboxylate protecting groups, enabling precise and efficient construction of complex molecular architectures. This compound is primarily needed by research scientists and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of piperidine-based drug candidates, including potential CNS agents and receptor modulators.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand and Catalyst Precursor: Serves as a precursor for sophisticated ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the creation of specialty polymers and advanced organic materials with specific fluorinated properties.
• Chemical Biology Probe Development: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects requiring functionalized piperidine scaffolds.

Basic Information

Product Name	1-tert-Butyl 4-(Pentafluorophenyl) Piperidine-1,4-Dicarboxylate
CAS No.	294885-28-2
Molecular Formula	C17H18F5NO4
Molecular Weight	395.33 g/mol
Synonyms	1-tert-Butoxycarbonyl-4-(pentafluorobenzoyl)piperidine; 4-(Pentafluorobenzoyl)piperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-(pentafluorobenzoyl)piperidine-1-carboxylate; 1-Boc-4-(pentafluorobenzoyl)piperidine; Boc-Piperidine-4-(pentafluorophenyl)carboxylate; CAS 294885-28-2; 1-(tert-Butoxycarbonyl)-4-(pentafluorobenzoyl)piperidine
EINECS	Contact for details

Quality Control

Our 1-tert-Butyl 4-(Pentafluorophenyl) Piperidine-1,4-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.