Description

5-(2,5-Dioxopyrrolidin-1-Yl) 1-Methyl Palmitoyl-L-Glutamate is a specialized, high-purity chemical intermediate designed for advanced synthesis. This compound matters for its role as a key building block in the development of sophisticated, functional molecules, offering precise reactivity for conjugation and derivatization. It is primarily needed by research and development teams in the pharmaceutical, cosmetic, and advanced materials sectors seeking to create novel peptide-based or lipid-conjugated products.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in peptide and prodrug development.
• Cosmetic & Personal Care Actives: Used in the formulation of advanced anti-aging and skin-repair ingredients, such as lipopeptides and ceramide analogs.
• Bioconjugation & Linker Chemistry: Serves as a reactive linker for attaching functional groups (e.g., fluorescent dyes, targeting ligands) to peptides, proteins, or nanoparticles.
• Biomaterials Research: Employed in the creation of functionalized polymers and hydrogels for controlled drug delivery and tissue engineering applications.
• Chemical Biology Probes: Utilized to develop probes for studying enzyme activity, protein-protein interactions, and cellular uptake mechanisms.
• High-Purity Reference Standard: Supplied as a certified reference material for analytical method development and quality control in regulated industries.

Basic Information

Product Name	5-(2,5-Dioxopyrrolidin-1-Yl) 1-Methyl Palmitoyl-L-Glutamate
CAS No.	294855-90-6
Molecular Formula	C27H44N2O7
Molecular Weight	508.65 g/mol
Synonyms	1-Methyl Palmitoyl-L-Glutamate N-Hydroxysuccinimide Ester; Palmitoyl-L-Glutamic Acid 1-Methyl Ester N-Succinimidyl Ester; N-(Palmitoyl)-L-glutamic Acid 1-Methyl Ester N-Succinimidyl Ester; N-Succinimidyl 1-Methyl Palmitoyl-L-glutamate; N-Hydroxysuccinimide Ester of 1-Methyl Palmitoyl-L-glutamate; Palmitoyl-Glu(OMe)-OSu; Lipopeptide NHS Ester (C16); N-[(1S)-1-Methoxy-1-oxo-5-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]pentyl]hexadecanamide
EINECS	Contact for details

Quality Control

Our 5-(2,5-Dioxopyrrolidin-1-Yl) 1-Methyl Palmitoyl-L-Glutamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.