Description

5-tert-Butyl-2H-Pyrazole-3-Carboxylic Acid Ethyl Ester is a high-purity pyrazole derivative ester, serving as a critical advanced intermediate in organic synthesis. Its value lies in providing a functionalized pyrazole core for constructing complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and production of next-generation pesticides and herbicides, leveraging the pyrazole moiety's bioactivity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Material Science Precursor: Potential intermediate in the synthesis of specialized polymers or ligands for catalytic systems.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	5-tert-Butyl-2H-Pyrazole-3-Carboxylic Acid Ethyl Ester
CAS No.	294852-57-6
Molecular Formula	C₁₀H₁₆N₂O₂
Molecular Weight	196.25 g/mol
Synonyms	Ethyl 5-tert-butyl-1H-pyrazole-3-carboxylate; 5-tert-Butyl-1H-pyrazole-3-carboxylic acid ethyl ester; 3-Carbethoxy-5-tert-butylpyrazole; 5-(1,1-Dimethylethyl)-1H-pyrazole-3-carboxylic acid ethyl ester; Ethyl 5-(tert-butyl)-1H-pyrazole-3-carboxylate; 294852-57-6; 5-tert-Butyl-2H-pyrazole-3-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 5-tert-Butyl-2H-Pyrazole-3-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.