Description

5-[Bis(2-Chloroethyl)Amino]-2-Benzofurancarboxylic Acid Ethyl Ester is a specialized synthetic intermediate of significant interest in advanced organic synthesis. This compound is valued for its bifunctional molecular architecture, which incorporates both a benzofuran core and a nitrogen mustard moiety, enabling its use in the development of complex bioactive molecules. It is primarily sought by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for the synthesis of novel therapeutic agents and as a key building block in heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A critical precursor in the research and development of novel drug candidates, particularly those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Serves as a versatile building block for constructing complex heterocyclic scaffolds with potential biological activity.
• Organic Synthesis Reagent: Used in academic and industrial laboratories for the synthesis of benzofuran derivatives and other fused ring systems.
• Bioconjugate Chemistry: Potential use in the development of antibody-drug conjugates (ADCs) or other targeted therapeutic platforms due to its reactive functional groups.
• Chemical Biology Probes: Can be utilized to create molecular probes for studying biological processes and protein interactions.

Basic Information

Product Name	5-[Bis(2-Chloroethyl)Amino]-2-Benzofurancarboxylic Acid Ethyl Ester
CAS No.	294174-66-6
Molecular Formula	C₁₅H₁₇Cl₂NO₃
Molecular Weight	330.21 g/mol
Synonyms	Ethyl 5-[bis(2-chloroethyl)amino]-1-benzofuran-2-carboxylate; 5-[Bis(2-chloroethyl)amino]-2-benzofurancarboxylic acid ethyl ester; 2-Benzofurancarboxylic acid, 5-[bis(2-chloroethyl)amino]-, ethyl ester; 5-(Bis(2-chloroethyl)amino)benzofuran-2-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our 5-[Bis(2-Chloroethyl)Amino]-2-Benzofurancarboxylic Acid Ethyl Ester is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.