Description

3-(Azidomethyl)-2-Bromoquinoline is a specialized halogenated quinoline derivative functionalized with an azidomethyl group, serving as a versatile and high-value synthetic intermediate. This compound is engineered to enable efficient cross-coupling reactions and click chemistry, facilitating the rapid construction of complex molecular architectures. It is primarily sought after by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Research: Used in creating new fungicides, herbicides, and insecticides with enhanced activity profiles.
• Click Chemistry Substrate: The azide group enables efficient, selective Huisgen cycloaddition reactions for bioconjugation and polymer functionalization.
• Material Science: Precursor for synthesizing functionalized quinoline-based polymers, ligands, and organic electronic materials.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Sonogashira, and Buchwald-Hartwig amination reactions.
• Chemical Biology Probes: Used to develop activity-based probes and fluorescent tags for studying biological systems.

Basic Information

Product Name	3-(Azidomethyl)-2-Bromoquinoline
CAS No.	292077-57-7
Molecular Formula	C₁₀H₇BrN₄
Molecular Weight	263.10 g/mol
Synonyms	2-Bromo-3-(azidomethyl)quinoline; 3-Azidomethyl-2-bromoquinoline; Quinoline, 2-bromo-3-(azidomethyl)-; 2-Bromo-3-quinolinemethyl azide; 292077-57-7; Azidomethyl Bromoquinoline; Bromo Azidomethylquinoline
EINECS	Contact for details

Quality Control

Our 3-(Azidomethyl)-2-Bromoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide detailed Certificates of Analysis (COA) with every shipment, ensuring traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to the light-sensitive and potentially shock-sensitive nature of organic azides, handle and store with appropriate precautions, away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.