Description

6-o-(Tert.-Butyldiphenylsilyl)-1,2,3,4-Tetra-o-Benzyl-β-D-Glucopyranose CAS NO 291527-97-4 is a sophisticated, multi-protected carbohydrate derivative that serves as a critical advanced intermediate in complex organic synthesis. Its value lies in providing precise stereochemical control and selective deprotection pathways, enabling the efficient construction of biologically active molecules. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries, particularly for developing novel glycosides, glycoconjugates, and other carbohydrate-based therapeutics.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of complex carbohydrate-based drugs, including antiviral and anticancer agents.
• Glycoconjugate Synthesis: Used in the preparation of glycoproteins, glycolipids, and other biologically relevant conjugates for research and therapeutic applications.
• Oligosaccharide Assembly: Serves as a protected glycosyl donor or acceptor in the stepwise construction of specific oligosaccharide sequences.
• Chemical Biology Probes: Enables the creation of labeled carbohydrate probes for studying glycosylation processes and carbohydrate-protein interactions.
• Agrochemical Development: Acts as an intermediate in the synthesis of novel, bioactive carbohydrate-derived crop protection agents.
• Process Chemistry & Scale-up: Provides a reliable and well-characterized intermediate for the kilogram-scale production of target molecules under GMP or non-GMP conditions.

Basic Information

Product Name	6-o-(Tert.-Butyldiphenylsilyl)-1,2,3,4-Tetra-o-Benzyl-β-D-Glucopyranose
CAS No.	291527-97-4
Molecular Formula	C46H54O6Si
Molecular Weight	731.01 g/mol
Synonyms	1,2,3,4-Tetra-O-benzyl-6-O-(tert-butyldiphenylsilyl)-β-D-glucopyranose; 6-O-TBDPS-1,2,3,4-tetra-O-benzyl-β-D-glucopyranose; β-D-Glucopyranose, 6-O-[(1,1-dimethylethyl)diphenylsilyl]-1,2,3,4-tetra-O-(phenylmethyl)-; TBDPS-protected tetra-O-benzyl glucose; Tetra-O-benzyl-6-O-tert-butyldiphenylsilyl-β-D-glucopyranose; Protected β-D-glucose derivative; CAS 291527-97-4
EINECS	Contact for details

Quality Control

Every batch of our 6-o-(Tert.-Butyldiphenylsilyl)-1,2,3,4-Tetra-o-Benzyl-β-D-Glucopyranose is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, meeting the exacting standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting key parameters such as assay (HPLC), chiral purity, and impurity profile. Specifications can be aligned with research-grade or GMP-grade requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity	≥ 99.0% β-anomer
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.