Description

1,6-Dioxaspiro[4.5]Dec-7-Ene-7-Methanol,9-Ethoxy-,(5R,9R)-(9Ci) is a high-purity, stereochemically defined spirocyclic compound, identified by CAS number 289891-20-9. This molecule serves as a sophisticated chiral building block and synthetic intermediate, offering significant value in the development of complex, biologically active molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in areas requiring complex stereochemistry.
• Asymmetric Synthesis: Utilized as a building block in stereoselective reactions to construct complex molecular architectures with high enantiomeric purity.
• Medicinal Chemistry Research: Employed in lead optimization and structure-activity relationship (SAR) studies to explore new chemical space for drug discovery.
• Agrochemical Synthesis: Serves as an intermediate in the development of advanced crop protection agents with specific modes of action.
• Fine Chemical Production: Used in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring high stereochemical fidelity.
• Academic & Industrial R&D: A valuable tool for methodological development in organic synthesis and catalysis research.

Basic Information

Product Name	1,6-Dioxaspiro[4.5]Dec-7-Ene-7-Methanol,9-Ethoxy-,(5R,9R)-(9Ci)
CAS No.	289891-20-9
Molecular Formula	C12H18O4
Molecular Weight	226.27 g/mol
Synonyms	(5R,9R)-9-Ethoxy-1,6-dioxaspiro[4.5]dec-7-ene-7-methanol; (5R,9R)-9-Ethoxy-1,6-dioxaspiro[4.5]dec-7-ene-7-carbinol; 7-(Hydroxymethyl)-9-ethoxy-1,6-dioxaspiro[4.5]dec-7-ene, (5R,9R)-; 289891-20-9; (5R,9R)-9-Ethoxy-7-(hydroxymethyl)-1,6-dioxaspiro[4.5]dec-7-ene; Spirocyclic ethoxy methanol derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with a typical purity of ≥97% (by HPLC), with specifications tailored for research and process development use. Certificates of Analysis (COA) detailing identity, purity (HPLC/GC), chiral purity, and residual solvent levels are available upon request. Our quality system supports development under cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound may be sensitive to moisture and oxidation; for long-term storage, consider an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.