Description

Spiro[4.4]Nonan-1-One, 6-Amino-, (5S,6S)- (9Ci) is a chiral, spirocyclic organic compound featuring a unique bicyclic framework with an amino functional group. This specific stereochemistry makes it a valuable and versatile chiral building block for the synthesis of complex molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries. The compound's rigid spiro structure and defined stereocenters are crucial for creating molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) drugs and other therapeutics requiring complex stereochemistry.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides where its specific three-dimensional shape can enhance target specificity and efficacy.
• Asymmetric Catalysis Ligand Precursor: The amino group and chiral backbone can be modified to develop novel ligands for asymmetric synthesis, enabling the production of enantiomerically pure compounds.
• Material Science Research: Investigated as a monomer or building block for creating novel polymers with unique thermal or mechanical properties derived from its rigid spiro structure.
• Chemical Biology Probe Development: Utilized in the design and synthesis of molecular probes to study biological pathways and enzyme functions.

Basic Information

Product Name	Spiro[4.4]Nonan-1-One, 6-Amino-, (5S,6S)- (9Ci)
CAS No.	289665-71-0
Molecular Formula	C9H15NO
Molecular Weight	153.22 g/mol
Synonyms	(5S,6S)-6-Aminospiro[4.4]nonan-1-one; (5S,6S)-6-Amino-spiro[4.4]nonane-1-one; 6-Amino-spiro[4.4]nonan-1-one, (5S,6S)-; Spiro[4.4]nonan-1-one, 6-amino-, (5S,6S)-; (5S,6S)-6-Azaspiro[4.4]nonan-7-one (tautomeric form); 289665-71-0; (5S-cis)-6-Aminospiro[4.4]nonan-1-one
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Every batch is characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all specifications and test results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation, especially after opening the original container. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.