Description

Zinpyr-1 is a highly selective and sensitive fluorescent probe designed for the detection and imaging of intracellular zinc ions (Zn²⁺). This compound matters because it provides researchers with a powerful tool for visualizing zinc dynamics in biological systems, which is crucial for understanding its role in neurotransmission, immune function, and cellular signaling. It is needed by scientists and professionals in life science research, pharmaceutical development, and diagnostic applications who require reliable and specific zinc sensing.

Application

• Neuroscience Research: Imaging of synaptic zinc pools and studying its role in neuronal communication and plasticity.
• Cell Biology Studies: Detection of labile zinc ions in live cells and organelles to investigate metallostasis and signaling pathways.
• Immunology Research: Monitoring zinc fluctuations in immune cells, such as macrophages and neutrophils, during activation and inflammation.
• Pharmaceutical Screening: Used as a tool compound in assays to discover and evaluate drugs that modulate zinc homeostasis.
• Diagnostic Probe Development: Serving as a core fluorescent scaffold for developing next-generation diagnostic sensors for zinc-related pathologies.
• Biochemical Assays: Quantitative determination of free zinc concentrations in buffer solutions and biological samples.

Basic Information

Product Name	Zinpyr-1
CAS No.	288574-78-7
Molecular Formula	C₄₄H₄₄N₆O₆
Molecular Weight	752.87 g/mol
Synonyms	Zinpyr-1; ZP1; 2,2'-[2-(2-{2-[Bis(2-pyridinylmethyl)amino]ethoxy}ethoxy)ethylimino]bis[N-(2-pyridinylmethyl)acetamide]; N,N,N',N'-Tetrakis(2-pyridylmethyl)-2,2'-(ethylenedioxy)bis(ethylamine); Zinc fluorescent probe ZP1; Zinpyr1; Zinpyr 1
EINECS	Contact for details

Quality Control

Our Zinpyr-1 is produced under strict quality management protocols to ensure batch-to-batch consistency and high performance in sensitive applications. Each lot undergoes rigorous analytical testing, including HPLC for purity verification and spectroscopic characterization to confirm identity and functionality. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and performance. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Fluorescence Properties	Ex/Em ~ 500/530 nm (Zinc-bound form)
Solubility	Soluble in DMSO, DMF; sparingly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.