Description

Cyclopropaneacetic Acid, 2-Acetyl-, Methyl Ester, (1R,2R)-Rel- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures with precise three-dimensional control, which is critical for developing bioactive molecules. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for applications in asymmetric synthesis, medicinal chemistry, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel Active Pharmaceutical Ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery.
• Asymmetric Synthesis: Used as a building block in stereoselective reactions to introduce the cyclopropane moiety, a valuable structural motif known to enhance metabolic stability and conformational rigidity.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical space and improve drug candidate profiles.
• Agrochemical Synthesis: Serves as an intermediate in the development of advanced pesticides and herbicides where the chiral cyclopropane structure can influence biological activity and selectivity.
• Fine Chemical Production: Utilized in the custom synthesis of complex, high-value specialty chemicals for various industrial and research applications.
• Academic & Institutional Research: A valuable reagent for methodological development in organic chemistry and catalysis studies within university and government laboratories.

Basic Information

Product Name	Cyclopropaneacetic Acid, 2-Acetyl-, Methyl Ester, (1R,2R)-Rel- (9Ci)
CAS No.	288153-50-4
Molecular Formula	C9H12O3
Molecular Weight	168.19 g/mol
Synonyms	(1R,2R)-rel-2-Acetylcyclopropaneacetic acid methyl ester; Methyl (1R,2R)-rel-2-acetylcyclopropaneacetate; Methyl 2-(2-acetylcyclopropyl)acetate, (1R,2R)-rel-; 2-Acetylcyclopropaneacetic acid methyl ester, (1R,2R)-rel-; (rel-(1R,2R))-Methyl 2-acetylcyclopropaneacetate; Cyclopropaneacetic acid, 2-acetyl-, methyl ester, (1R,2R)-rel-
EINECS	Contact for details

Quality Control

Our Cyclopropaneacetic Acid, 2-Acetyl-, Methyl Ester, (1R,2R)-Rel- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de (diastereomeric excess)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.