Description

tert-Butyl 2-(4-Bromophenoxy)Acetate is a high-purity organic building block and pharmaceutical intermediate of significant commercial importance. This compound is valued for its role in the synthesis of more complex molecules, particularly in medicinal chemistry and advanced material science. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system and inflammatory diseases.
• Agrochemical Synthesis: Used in the preparation of advanced herbicides and plant growth regulators, leveraging the phenoxyacetic acid moiety.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and transition metal complexes.
• Polymer Chemistry: Employed in the synthesis of monomers for specialty polymers with tailored thermal or optical properties.
• Organic Synthesis Building Block: The tert-butyl ester and bromophenoxy groups offer orthogonal reactivity for sequential functionalization in multi-step synthetic routes.
• Material Science Research: Investigated for the development of organic semiconductors and liquid crystalline materials due to its aromatic and ether linkages.

Basic Information

Product Name	tert-Butyl 2-(4-Bromophenoxy)Acetate
CAS No.	282116-88-5
Molecular Formula	C12H15BrO3
Molecular Weight	287.15 g/mol
Synonyms	2-(4-Bromophenoxy)acetic acid tert-butyl ester; 4-Bromophenoxyacetic acid tert-butyl ester; tert-Butyl (4-bromophenoxy)acetate; Acetic acid, 2-(4-bromophenoxy)-, 1,1-dimethylethyl ester; 1,1-Dimethylethyl [2-(4-bromophenoxy)]acetate; (4-Bromophenoxy)acetic Acid tert-Butyl Ester; t-Butyl 2-(p-bromophenoxy)acetate
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-(4-Bromophenoxy)Acetate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.