Description

Diethyl 2-(Hydroxymethyl)-2-Phenylmalonate is a versatile and high-purity organic building block, specifically a substituted malonate ester. This compound is valued for its bifunctional reactivity, featuring both a hydroxyl group and two ester groups, which makes it a critical intermediate in sophisticated multi-step organic syntheses. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of active pharmaceutical ingredients (APIs) and complex specialty molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs), particularly those requiring chiral or functionalized malonate frameworks.
• Fine Chemical Synthesis: Serves as a versatile building block for constructing complex organic compounds in research and development laboratories.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators that utilize malonate-derived structures.
• Material Science Precursor: Potential monomer or intermediate for synthesizing specialized polymers and functional materials.
• Academic & Industrial R&D: Employed in methodological studies and process chemistry for developing new synthetic routes.

Basic Information

Product Name	Diethyl 2-(Hydroxymethyl)-2-Phenylmalonate
CAS No.	278791-10-9
Molecular Formula	C14H18O5
Molecular Weight	266.29 g/mol
Synonyms	2-(Hydroxymethyl)-2-phenylmalonic acid diethyl ester; Diethyl (hydroxymethyl)(phenyl)propanedioate; 2-Phenyl-2-(hydroxymethyl)malonic acid diethyl ester; Propanedioic acid, 2-(hydroxymethyl)-2-phenyl-, diethyl ester; Ethyl 2-(hydroxymethyl)-2-phenylmalonate
EINECS	Contact for details

Quality Control

Our Diethyl 2-(Hydroxymethyl)-2-Phenylmalonate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Custom purity grades, including research and GMP standards, are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product quality and stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.