Description

tert-Butyl 5,6-Dichloropyridin-3-Ylcarbamate is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated pyridine structure. This compound is of significant value in modern organic synthesis, serving as a critical building block for the development of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging its dichloropyridine moiety.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the multi-step synthesis of final API compounds requiring this specific carbamate-protected intermediate.
• Custom Synthesis Building Block: Supplied to fine chemical companies for use in contract research and custom synthesis projects.

Basic Information

Product Name	tert-Butyl 5,6-Dichloropyridin-3-Ylcarbamate
CAS No.	275383-96-5
Molecular Formula	C10H12Cl2N2O2
Molecular Weight	263.12 g/mol
Synonyms	5,6-Dichloro-3-pyridinylcarbamic acid 1,1-dimethylethyl ester; tert-Butyl (5,6-dichloropyridin-3-yl)carbamate; 3-((tert-Butoxycarbonyl)amino)-5,6-dichloropyridine; 5,6-Dichloro-3-((tert-butoxycarbonyl)amino)pyridine; Boc-5,6-dichloro-3-aminopyridine; (5,6-Dichloro-3-pyridinyl)-N-Boc-amine; tert-Butyl N-(5,6-dichloropyridin-3-yl)carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl 5,6-Dichloropyridin-3-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.