Description

Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, Methyl Ester, (2R)- (9Ci) is a high-purity, chiral bicyclic olefin derivative, specifically the (R)-enantiomer of the methyl ester. This compound is a critical advanced pharmaceutical intermediate (API) and a versatile chiral building block for asymmetric synthesis. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates, particularly those requiring the rigid bicyclo[2.2.1]heptene scaffold for specific biological activity.
• Asymmetric Catalysis: Serves as a precursor or ligand component in the development of chiral catalysts for enantioselective reactions.
• Agrochemical Synthesis: Used in the research and production of chiral pesticides and herbicides where stereochemistry impacts efficacy and environmental profile.
• Material Science Research: Employed as a monomer or cross-linking agent in the development of novel polymers with unique thermal or mechanical properties.
• Organic Synthesis Building Block: Utilized in Diels-Alder reactions and other cycloadditions to construct complex polycyclic frameworks in natural product and fine chemical synthesis.
• Flavor & Fragrance Industry: Potential intermediate for the synthesis of high-value, stereochemically defined aroma chemicals.

Basic Information

Product Name	Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, Methyl Ester, (2R)- (9Ci)
CAS No.	274255-60-6
Molecular Formula	C10H14O2
Molecular Weight	166.22 g/mol
Synonyms	(2R)-Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid methyl ester; (R)-2-Methoxycarbonylbicyclo[2.2.1]hept-5-ene; Methyl (1R,4R)-bicyclo[2.2.1]hept-5-ene-2-carboxylate; (R)-Norbornene methyl ester; (2R)-2-Carbomethoxynorbornene; (R)-Methyl 5-norbornene-2-carboxylate; (1R,4R)-5-Norbornene-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, Methyl Ester, (2R)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC to ensure high enantiomeric excess (e.e.) and purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing identity, purity, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.